BIOL 306
Cellular Regulatory Mechanisms
Last Offered Spring 2009
Division III
This course is not offered in the current catalog

This course explores the regulation of cellular function and gene expression from a perspective that integrates current paradigms in molecular genetics, signal transduction, and genomics. Topics include: transcriptional and post-transcriptional control, chromatin regulation of gene silencing and imprinting, chromosome instability, prions and other self-perpetuating protein conformations, protein degradation, and organellar and cytoskeletal dynamics. A central feature of the course will be discussion of articles from the primary literature. The laboratory will consist of a semester-long research project that integrates recombinant DNA techniques with genomic tools to investigate unanswered questions in eukaryotic cell biology using yeast as a model organism.