BIOL 416
Epigenetics Spring 2015
Division III
This is not the current course catalog

Class Details

After decades of studies emphasizing the role of DNA in heredity, scientists are now turning their attention from genetics to a variety of heritable phenomena that fall under the heading of epigenetics, heritable changes that do not result from an alteration in DNA sequence. Research reveals that stable changes in cell function can result from, for example, stable changes in protein conformation, protein modification, DNA methylation, or the location of a molecule within the cell. Using readings from the primary literature, we will explore the epigenetic nature and molecular mechanisms underlying a diverse array of phenomena such as prion propagation, genetic imprinting, dosage compensation, transvection, centromere formation, vernalization, and programmed genome rearrangements. The significance of epigenetic processes for development, evolution, and human health will be discussed.
The Class: Format: discussion, three hours per week
Limit: 12
Expected: 12
Class#: 3369
Grading: yes pass/fail option, yes fifth course option
Requirements/Evaluation: evaluation will be based on class participation and several short papers
Prerequisites: BIOL 202; open to juniors and seniors
Enrollment Preferences: senior Biology majors who have not taken a 400-level course, then to juniors
Unit Notes: does not satisfy the distribution requirement in the Biology major
Distributions: Division III
Attributes: BIMO Interdepartmental Electives

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