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This course is a continuation of Chemistry 156 and it concludes the systematic study of the common classes of organic compounds with emphasis on theories of structure and reactivity. Specific topics include radical chemistry, an introduction to mass spectrometry and ultraviolet spectroscopy, the theory and chemical reactivity of conjugated and aromatic systems, the concepts of kinetic and thermodynamic control, an extensive treatment of the chemistry of the carbonyl group, alcohols, ethers, polyfunctional compounds, the concept of selectivity, the fundamentals of organic synthesis, an introduction to carbohydrates, carboxylic acids and derivatives, acyl substitution reactions, amines, and an introduction to amino acids, peptides, and proteins. The coordinated laboratory work includes application of the techniques learned in the introductory level laboratory, along with new functional group analyses, to the separation and identification of several unknown samples. Skills in analyzing NMR, IR, and MS data are practiced and further refined.
Format: lecture/conference; Chemistry 251 will have no laboratory component. Students will instead enroll in mandatory conference sections, which will be held online. Lectures will be offered in-person and recorded for those learning remotely. Lectures will also be recorded in a second format that is optimized for remote learning, and these recordings will also be available to all enrolled students. In-person lectures will be capped, with preference given to students enrolling as one of their three initial courses.
Grading: no pass/fail option,
no fifth course option
midterm exams, problem sets, and a final exam
CHEM 156 or permission of instructor
seniors, juniors, then sophomores
BIMO Required Courses