This course introduces the foundational concepts of biochemistry with an emphasis on the structure and function of biological macromolecules. Specifically, the structure of proteins and nucleic acids are examined in detail in order to determine how their chemical properties and their biological behavior result from those structures. Other topics covered include catalysis, enzyme kinetics, mechanism and regulation; the molecular organization of biomembranes; and the flow of information from nucleic acids to proteins. In addition, the principles and applications of the methods used to characterize macromolecules in solution and the interactions between macromolecules are discussed. The in-person laboratory provides further opportunity to study macromolecules and to learn the fundamental experimental techniques of biochemistry including electrophoresis, chromatography, and principles of enzymatic assays. A laboratory section will also be provided for remote students, which will examine similar topics and techniques through literature and data analysis.
Format: lecture/laboratory; Synchronous lectures (2x 75-minute meetings per week) and labs, two hours per week. Enrollment in the appropriate laboratory section is required for both in-person and remote students.
Grading: no pass/fail option,
no fifth course option
Quizzes, a midterm exam, a final exam, problem sets and performance in the laboratories including lab reports
BIOL 101 and CHEM 251/255 and CHEM 155/256
junior and senior Biology and Chemistry majors and BIMO concentrators
does not satisfy the distribution requirement for the Biology major; cannot be counted towards the Biology major in addition to BIOL 222
This course is cross-listed and the prefixes carry the following divisional credit:
This course fulfills the QFR requirement with regular problem sets in which quantitative/formal reasoning skills are practiced.
BIMO Required Courses