CHEM 344
Physical Organic Chemistry Spring 2022
Division III

Class Details

The structure of a molecule is inherently linked to its reactivity, and these correlations form the basis for understanding organic reaction mechanisms. This course advances the understanding from previous organic courses through a detailed examination of the concepts that underlie these structure/reactivity relationships, including molecular strain and stability, acid/base chemistry, steric and electronic effects, and aromaticity. These concepts will also be explored in the context of specific classes of reaction mechanisms. Classical and modern experimental and theoretical tools used to elucidate reaction mechanisms will also be presented, including reaction kinetics, isotope effects, and linear free energy relationships. By studying the primary literature, we will see how these experiments have been applied to the elucidation of reaction mechanism, while also learning to design a set of experiments for study of mechanisms of contemporary interest.
The Class: Format: lecture/laboratory; lecture, three times per week and laboratory, four hours per week
Limit: 7/lab
Expected: 14
Class#: 3091
Grading: no pass/fail option, no fifth course option
Requirements/Evaluation: problem sets, exams, laboratory reports, presentations, and class participation
Prerequisites: CHEM 155 or CHEM 256 and 251/255
Enrollment Preferences: Chemistry majors: seniors, juniors, sophomores
Distributions: Division III
Attributes: BIMO Interdepartmental Electives

Class Grid

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