CHEM 342
Synthetic Organic Chemistry Spring 2024
Division III

Class Details

The origins of organic chemistry are to be found in the chemistry of living things and the emphasis of this course is on the chemistry of naturally-occurring compounds. This course presents the logic and practice of chemical total synthesis while stressing the structures, properties and preparations of terpenes, polyketides and alkaloids. Modern synthetic reactions are surveyed with an emphasis on the stereochemical and mechanistic themes that underlie them. To meet the requirements for the semester’s final project, each student chooses an article from the recent synthetic literature and then analyzes the logic and strategy involved in the published work in a final paper. A summary of this paper is also presented to the class in a short seminar. There will be no laboratory component in 2022. Instead, one of the three class meetings each week will focus on discussion and presentation of reactions, mechanisms, and syntheses from the chemical literature.
The Class: Format: lecture; lecture, three hours per week and conference, 1.5 hours per week
Limit: 16
Expected: 16
Class#: 3139
Grading: no pass/fail option, no fifth course option
Requirements/Evaluation: problem sets, midterm exams, class participation, class presentations, and a final project
Prerequisites: CHEM 155 or CHEM 256 and CHEM 251 or permission of instructor; or CHEM 200 and CHEM 242 or permission of instructor
Enrollment Preferences: Chemistry majors, seniors and juniors
Distributions: Division III

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